Description

Ethyl 5-Cyano-2-Phenyl-6-[4-(2-Pyridinyl)Piperazino]Nicotinate is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel drug candidates targeting central nervous system and other therapeutic areas. It is essential for pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex target molecules.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and process development.
• Academic & Institutional Research: Utilized in university and institutional labs for pharmacological and biochemical research.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Item	Detail
Product Name	Ethyl 5-Cyano-2-Phenyl-6-[4-(2-Pyridinyl)Piperazino]Nicotinate
CAS No.	477866-20-9
Molecular Formula	C24H22N6O2
Molecular Weight	426.47 g/mol
Synonyms	Ethyl 5-Cyano-2-Phenyl-6-(4-pyridin-2-ylpiperazin-1-yl)nicotinate; 477866-20-9; Nicotinic acid, 5-cyano-2-phenyl-6-(4-(2-pyridinyl)-1-piperazinyl)-, ethyl ester; Ethyl 5-cyano-2-phenyl-6-(4-(pyridin-2-yl)piperazin-1-yl)nicotinate; 6-(4-(Pyridin-2-yl)piperazin-1-yl)-2-phenyl-5-cyanonicotinic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Cyano-2-Phenyl-6-[4-(2-Pyridinyl)Piperazino]Nicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your internal specifications and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.