Description

Ethyl 5-Cyano-2-Phenyl-6-(4-Phenylpiperazino)Nicotinate is a sophisticated, high-value pharmaceutical intermediate and research chemical. This compound is critical for the synthesis of novel drug candidates, particularly in the development of central nervous system (CNS) and receptor-targeted therapeutics. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and advanced fine chemical manufacturers engaged in innovative drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential neuroactive compounds and receptor modulators.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Biology: Serves as a probe or precursor in the study of biological pathways and target validation.
• Reference Standard: Utilized as an analytical standard for quality control and method development in API manufacturing.
• Academic Research: Employed in university and institutional labs for advanced organic synthesis and pharmacological research.
• Custom Synthesis: Starting material for the contract manufacturing of specialized, non-commercial chemical entities.

Basic Information

Product Name	Ethyl 5-Cyano-2-Phenyl-6-(4-Phenylpiperazino)Nicotinate
CAS No.	477866-19-6
Molecular Formula	C25H24N4O2
Molecular Weight	412.49 g/mol
Synonyms	Ethyl 5-cyano-2-phenyl-6-(4-phenyl-1-piperazinyl)nicotinate; 5-Cyano-2-phenyl-6-(4-phenylpiperazin-1-yl)nicotinic acid ethyl ester; 6-(4-Phenylpiperazin-1-yl)-2-phenylnicotinonitrile-5-carboxylic acid ethyl ester; Nicotinic acid, 5-cyano-2-phenyl-6-(4-phenyl-1-piperazinyl)-, ethyl ester; CAS 477866-19-6
EINECS	Contact for details

Quality Control

Our Ethyl 5-Cyano-2-Phenyl-6-(4-Phenylpiperazino)Nicotinate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.