Description

Ethyl 5-Cyano-6-[4-(2-Fluorophenyl)Piperazino]-2-Phenylnicotinate is a high-value, multi-functional chemical intermediate featuring a complex nicotinate core substituted with cyano, fluorophenyl-piperazino, and phenyl groups. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical candidates, particularly those targeting central nervous system (CNS) disorders. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate to develop new therapeutic agents with potential neurological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of novel drug candidates, especially for neurological and psychiatric applications.
• Chemical Synthesis Building Block: Used in organic synthesis to construct complex heterocyclic molecules due to its reactive cyano and ester functional groups.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Potential use as a tool compound for probing biological pathways and enzyme interactions in vitro.

Basic Information

Product Name	Ethyl 5-Cyano-6-[4-(2-Fluorophenyl)Piperazino]-2-Phenylnicotinate
CAS No.	477866-17-4
Molecular Formula	C25H23FN4O2
Molecular Weight	430.48 g/mol
Synonyms	Ethyl 5-Cyano-6-(4-(2-fluorophenyl)piperazin-1-yl)-2-phenylnicotinate; 2-Phenyl-5-cyano-6-[4-(2-fluorophenyl)-1-piperazinyl]nicotinic Acid Ethyl Ester; Nicotinic acid, 5-cyano-6-[4-(2-fluorophenyl)-1-piperazinyl]-2-phenyl-, ethyl ester; 477866-17-4; UNII-9V8I2K165Y; 9V8I2K165Y
EINECS	Contact for details

Quality Control

Our Ethyl 5-Cyano-6-[4-(2-Fluorophenyl)Piperazino]-2-Phenylnicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.