Description

Ethyl 5-Cyano-6-[(2-Methoxybenzyl)Amino]-2-Phenylnicotinate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development for targeted therapies. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted small-molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Fine Chemical Synthesis: Serves as a precursor for more complex heterocyclic compounds in custom synthesis and contract manufacturing.
• Academic & Institutional R&D: Employed in university and research institute laboratories for developing new synthetic methodologies and exploring new chemical entities.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	Ethyl 5-Cyano-6-[(2-Methoxybenzyl)Amino]-2-Phenylnicotinate
CAS No.	477866-14-1
Molecular Formula	C23H21N3O3
Molecular Weight	387.44 g/mol
Synonyms	Ethyl 5-cyano-6-[(2-methoxybenzyl)amino]-2-phenylnicotinate; 2-Pyridinecarboxylic acid, 5-cyano-6-[(2-methoxybenzyl)amino]-2-phenyl-, ethyl ester; 5-Cyano-6-[(2-methoxybenzyl)amino]-2-phenylnicotinic acid ethyl ester; Ethyl 6-[(2-methoxybenzyl)amino]-5-cyano-2-phenylnicotinate; 477866-14-1; UNII-9Z5Q2F9K6F
EINECS	Contact for details

Quality Control

Our Ethyl 5-Cyano-6-[(2-Methoxybenzyl)Amino]-2-Phenylnicotinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure compliance with ICH guidelines. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions or inert atmosphere to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.