Description

Ethyl 5-Cyano-6-[(2,4-Dichlorobenzyl)Amino]-2-Phenylnicotinate is a high-purity, advanced pharmaceutical intermediate characterized by its specific nicotinate ester and dichlorobenzylamino functional groups. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in areas targeting specific enzyme inhibition.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the biological activity and pharmacokinetic properties of lead compounds.
• API Development: Serves as a precursor in the multi-step synthesis of complex target molecules for preclinical and clinical evaluation.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.
• Biochemical Tool Compound: Utilized in biochemical assays to study biological pathways and identify new therapeutic targets.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	Ethyl 5-Cyano-6-[(2,4-Dichlorobenzyl)Amino]-2-Phenylnicotinate
CAS No.	477866-13-0
Molecular Formula	C22H17Cl2N3O2
Molecular Weight	426.30 g/mol
Synonyms	Ethyl 5-Cyano-6-((2,4-dichlorobenzyl)amino)-2-phenylnicotinate; 2-Pyridinecarboxylic acid, 5-cyano-6-[(2,4-dichlorophenyl)methyl]amino]-2-phenyl-, ethyl ester; 477866-13-0; Ethyl 5-cyano-6-[(2,4-dichlorobenzyl)amino]-2-phenylpyridine-3-carboxylate; 5-Cyano-6-[(2,4-dichlorobenzyl)amino]-2-phenylnicotinic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Cyano-6-[(2,4-Dichlorobenzyl)Amino]-2-Phenylnicotinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.