Description

Ethyl 6-[(4-Chlorobenzyl)Amino]-5-Cyano-2-Phenylnicotinate is a high-value, multi-functional chemical intermediate with a complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical compounds and agrochemicals, enabling the development of new active ingredients. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel molecules with specific biological activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, or fungicides where the chlorobenzyl and cyano groups confer specific bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• Specialty Fine Chemicals: Employed in the production of advanced materials, dyes, or ligands for catalytic systems due to its functionalized pyridine core.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for the production of target molecules under cGMP or non-GMP conditions for clinical trials or commercial supply.

Basic Information

Product Name	Ethyl 6-[(4-Chlorobenzyl)Amino]-5-Cyano-2-Phenylnicotinate
CAS No.	477866-12-9
Molecular Formula	C22H18ClN3O2
Molecular Weight	391.85 g/mol
Synonyms	Ethyl 6-[(4-chlorophenyl)methyl]amino-5-cyano-2-phenylpyridine-3-carboxylate; 2-Pyridinecarboxylic acid, 6-[[(4-chlorophenyl)methyl]amino]-5-cyano-, ethyl ester; 6-[(4-Chlorobenzyl)amino]-5-cyano-2-phenylnicotinic acid ethyl ester; Ethyl 6-(4-chlorobenzylamino)-5-cyano-2-phenylnicotinate; Ethyl 6-(p-chlorobenzylamino)-5-cyano-2-phenylnicotinate; 477866-12-9; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our Ethyl 6-[(4-Chlorobenzyl)Amino]-5-Cyano-2-Phenylnicotinate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for advanced chemical intermediates. Certificates of Analysis (COA) detailing purity (typically by HPLC), identity (by IR, NMR), and impurity profiles are provided with every shipment. We support development and commercial projects with specifications tailored to your process needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.