Description

6-Chloro-5-[3-(Trifluoromethyl)Phenyl]-2,4-Pyridinediol is a high-value, multi-functional heterocyclic building block featuring a chloropyridine core substituted with a trifluoromethylphenyl group. This compound is critical for research and development in advanced organic synthesis, offering a unique scaffold for creating novel molecular architectures. It is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, as well as by specialty chemical manufacturers producing advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used as a building block for developing next-generation herbicides and fungicides, leveraging the bioactivity of the pyridine and trifluoromethyl motifs.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers and organic electronic materials.
• Chemical Biology Probe Development: Utilized in creating tool compounds for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, fluorinated heterocycles.

Basic Information

Product Name	6-Chloro-5-[3-(Trifluoromethyl)Phenyl]-2,4-Pyridinediol
CAS No.	477864-71-4
Molecular Formula	C12H7ClF3NO2
Molecular Weight	289.64 g/mol
Synonyms	6-Chloro-5-(3-(trifluoromethyl)phenyl)pyridine-2,4-diol; 2,4-Pyridinediol, 6-chloro-5-[3-(trifluoromethyl)phenyl]-; 5-(3-Trifluoromethylphenyl)-6-chloro-2,4-dihydroxypyridine; 6-Chloro-5-(α,α,α-trifluoro-m-tolyl)-2,4-pyridinediol
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-[3-(Trifluoromethyl)Phenyl]-2,4-Pyridinediol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.