Description

4-Oxo-5,6,7,8-Tetrahydro-4H-1,5,8A-Triaza-Azulene-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for complex small molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other specialized therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing complex heterocyclic libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Used in the research and process development stages for creating new Active Pharmaceutical Ingredients with potential kinase inhibitory or other targeted activities.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex organic molecules for client projects.
• Academic Research: Employed in university and institutional labs for studies in organic synthesis methodology and the development of new chemical entities.

Basic Information

Product Name	4-Oxo-5,6,7,8-Tetrahydro-4H-1,5,8A-Triaza-Azulene-2-Carboxylic Acid
CAS No.	477863-08-4
Molecular Formula	C9H9N3O3
Molecular Weight	207.19 g/mol
Synonyms	4-Oxo-5,6,7,8-tetrahydro-4H-1,5,8a-triazaazulene-2-carboxylic acid; 1,5,8a-Triazaazulene-2-carboxylic acid, 5,6,7,8-tetrahydro-4-oxo-; Tetrahydrotriazaazulene carboxylic acid derivative; CAS 477863-08-4; 4-Oxo-5,6,7,8-tetrahydro-1,5,8a-triazaazulene-2-carboxylic acid; 2-Carboxy-4-oxo-5,6,7,8-tetrahydro-4H-1,5,8a-triazaazulene
EINECS	Contact for details

Quality Control

Our 4-Oxo-5,6,7,8-Tetrahydro-4H-1,5,8A-Triaza-Azulene-2-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediates, ensuring traceability and documentation integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Single Maximum Impurity	≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.