Description

2-(1,1-Dioxo-1Lambda6,4-Thiazinan-4-Yl)-3-Methylbutanoic Acid is a specialized organic compound featuring a unique thiazinane dioxide moiety linked to a branched-chain carboxylic acid. This structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, particularly those targeting neurological or metabolic pathways.
• Medicinal Chemistry Research: Serves as a crucial building block for constructing complex molecular libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of proprietary compounds where the thiazinane dioxide group is integral to biological activity.
• Bioconjugation & Prodrug Development: The carboxylic acid functionality allows for conjugation to carriers or modification into ester prodrugs to enhance bioavailability.
• Chemical Biology Probes: Useful in the design and synthesis of chemical probes for investigating enzyme function and biological mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	2-(1,1-Dioxo-1Lambda6,4-Thiazinan-4-Yl)-3-Methylbutanoic Acid
CAS No.	477858-29-0
Molecular Formula	C9H15NO4S
Molecular Weight	233.28 g/mol
Synonyms	4-(1-Carboxy-2-methylpropyl)-1lambda6-thiazinane-1,1-dione; 3-Methyl-2-(1,1-dioxo-1lambda6-thiazinan-4-yl)butanoic acid; 2-(1,1-Dioxido-4-thiazinan-4-yl)-3-methylbutanoic acid; 3-Methyl-2-(1,1-dioxido-1,4-thiazinan-4-yl)butanoic acid; 2-(1,1-Dioxo-1,4-thiazinan-4-yl)-3-methylbutyric acid; 4-(2-Methyl-1-carboxypropyl)-1,1-dioxothiazinane
EINECS	Contact for details

Quality Control

Our production of 2-(1,1-Dioxo-1Lambda6,4-Thiazinan-4-Yl)-3-Methylbutanoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.