Description

2-(3-[4-Methyl-2-(2-Pyridinyl)-1,3-Thiazol-5-Yl]-3-Oxo-1-Phenylpropyl)Malononitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in medicinal chemistry and drug discovery pipelines. It is primarily utilized by R&D laboratories and manufacturing facilities in the pharmaceutical and biotechnology sectors seeking reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies for drug discovery programs.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and enzyme functions.
• Organic Synthesis: Acts as a versatile precursor for constructing complex nitrogen and sulfur-containing heterocycles in advanced organic synthesis.
• Agrochemical Research: Investigated as a potential intermediate for developing new crop protection agents with specific modes of action.

Basic Information

Product Name	2-(3-[4-Methyl-2-(2-Pyridinyl)-1,3-Thiazol-5-Yl]-3-Oxo-1-Phenylpropyl)Malononitrile
CAS No.	477847-84-0
Molecular Formula	C₂₁H₁₆N₄OS
Molecular Weight	372.44 g/mol
Synonyms	2-(3-(4-Methyl-2-(pyridin-2-yl)thiazol-5-yl)-3-oxo-1-phenylpropyl)malononitrile; 2-[3-[4-Methyl-2-(2-pyridinyl)-1,3-thiazol-5-yl]-3-oxo-1-phenylpropyl]propanedinitrile; 477847-84-0; Malononitrile, 2-[3-[4-methyl-2-(2-pyridinyl)-5-thiazolyl]-3-oxo-1-phenylpropyl]-
EINECS	Contact for details

Quality Control

Every batch of 2-(3-[4-Methyl-2-(2-Pyridinyl)-1,3-Thiazol-5-Yl]-3-Oxo-1-Phenylpropyl)Malononitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.