Description

(E)-1-(4-Methyl-2-Phenyl-1,3-Thiazol-5-Yl)-3-(4-Phenoxyphenyl)-2-Propen-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its distinct chalcone-thiazole hybrid structure. This compound is of significant commercial interest for its role as a critical building block in the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing bioactive molecules targeting inflammation, cancer, and metabolic disorders.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates with potential anti-inflammatory, anticancer, or kinase-inhibitory activity.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: Employed in biochemical assays to study specific biological pathways and protein interactions.
• Fine Chemical Synthesis: Acts as a specialized building block for constructing complex heterocyclic compounds in advanced organic synthesis.
• Academic Research: Utilized in universities and research institutes for investigating new organic reactions and photophysical properties of chalcone derivatives.

Basic Information

Product Name	(E)-1-(4-Methyl-2-Phenyl-1,3-Thiazol-5-Yl)-3-(4-Phenoxyphenyl)-2-Propen-1-One
CAS No.	477847-70-4
Molecular Formula	C25H19NO2S
Molecular Weight	397.49 g/mol
Synonyms	(E)-1-(4-Methyl-2-phenyl-1,3-thiazol-5-yl)-3-(4-phenoxyphenyl)prop-2-en-1-one; 2-Propen-1-one, 1-(4-methyl-2-phenyl-5-thiazolyl)-3-(4-phenoxyphenyl)-, (E)-; Chalcone-thiazole derivative; 477847-70-4; 4-Methyl-2-phenyl-5-[(1E)-3-(4-phenoxyphenyl)-3-oxo-1-propen-1-yl]-1,3-thiazole
EINECS	Contact for details

Quality Control

Our (E)-1-(4-Methyl-2-Phenyl-1,3-Thiazol-5-Yl)-3-(4-Phenoxyphenyl)-2-Propen-1-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.