Description

Ethyl 3-Amino-6-(4-Bromophenyl)-4-(Trifluoromethyl)Furo[2,3-B]Pyridine-2-Carboxylate is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters because it integrates a bromophenyl group, a trifluoromethyl moiety, and a furopyridine core, offering a unique scaffold for structure-activity relationship (SAR) studies and molecular diversification. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly for targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Research: Used as a key building block for developing new generations of herbicides, fungicides, and insecticides, leveraging the bioactivity of the furopyridine structure.
• Material Science: Employed in the research of advanced organic electronic materials, where the electron-withdrawing trifluoromethyl and bromine groups can tune electronic properties.
• Chemical Biology Probe Development: Acts as a scaffold for creating molecular probes to study enzyme function and protein-ligand interactions in biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects requiring complex heterocyclic chemistry.

Basic Information

Product Name	Ethyl 3-Amino-6-(4-Bromophenyl)-4-(Trifluoromethyl)Furo[2,3-B]Pyridine-2-Carboxylate
CAS No.	477320-34-6
Molecular Formula	C₁₇H₁₂BrF₃N₂O₃
Molecular Weight	429.19 g/mol
Synonyms	Ethyl 3-Amino-6-(4-bromophenyl)-4-(trifluoromethyl)furo[2,3-b]pyridine-2-carboxylate; 477320-34-6; 6-(4-Bromophenyl)-4-(trifluoromethyl)furo[2,3-b]pyridine-2-carboxylic acid ethyl ester, 3-amino-; 3-Amino-6-(4-bromophenyl)-4-(trifluoromethyl)furo[2,3-b]pyridine-2-carboxylic Acid Ethyl Ester; Ethyl 3-Amino-6-(p-bromophenyl)-4-(trifluoromethyl)furo[2,3-b]pyridine-2-carboxylate; Furo[2,3-b]pyridine-2-carboxylic acid, 3-amino-6-(4-bromophenyl)-4-(trifluoromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Amino-6-(4-Bromophenyl)-4-(Trifluoromethyl)Furo[2,3-B]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.