Description

1,2-Dihydro-4-Methyl-2-Oxo-6-p-Tolylpyridine-3-Carbonitrile is a high-value, heterocyclic organic compound featuring a pyridone core substituted with a tolyl group and a nitrile functionality. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block in synthetic organic chemistry. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Investigated for the creation of specialty polymers, liquid crystals, and organic electronic materials due to its rigid, conjugated structure.
• Chemical Synthesis: Acts as a versatile synthon in organic reactions, including cycloadditions and cross-coupling reactions, for constructing complex heterocycles.
• Biochemical Research: Employed in the study of enzyme inhibitors and the development of molecular probes for biological systems.

Basic Information

Product Name	1,2-Dihydro-4-Methyl-2-Oxo-6-p-Tolylpyridine-3-Carbonitrile
CAS No.	477320-28-8
Molecular Formula	C14H12N2O
Molecular Weight	224.26 g/mol
Synonyms	6-(4-Methylphenyl)-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile; 4-Methyl-2-oxo-6-(p-tolyl)-1,2-dihydropyridine-3-carbonitrile; 6-p-Tolyl-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile; CAS 477320-28-8; 1,2-Dihydro-4-methyl-2-oxo-6-(4-methylphenyl)-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 1,2-Dihydro-4-Methyl-2-Oxo-6-p-Tolylpyridine-3-Carbonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.