Description

6,10-Dioxaspiro[4.5]Decan-2-One,4-Ethyl-8,8-Dimethyl-,(4R)-(9Ci) is a high-purity, chiral spirocyclic compound that serves as a valuable synthetic intermediate. Its defined stereochemistry and unique molecular architecture make it a critical building block for the development of complex, biologically active molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use in asymmetric synthesis and the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring complex stereochemistry.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereoisomers are required for optimal efficacy and environmental profile.
• Flavor & Fragrance Chemistry: Serves as a precursor for synthesizing novel musk compounds and other complex aroma chemicals with specific olfactory properties.
• Material Science Research: Investigated as a monomer or building block for creating polymers with unique thermal or mechanical properties due to its rigid spirocyclic structure.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in catalytic systems designed for enantioselective transformations.
• Academic & Industrial R&D: A valuable tool for chemists exploring new synthetic methodologies and the construction of complex natural product analogs.

Basic Information

Product Name	6,10-Dioxaspiro[4.5]Decan-2-One,4-Ethyl-8,8-Dimethyl-,(4R)-(9Ci)
CAS No.	477293-78-0
Molecular Formula	C12H20O3
Molecular Weight	212.29 g/mol
Synonyms	(4R)-4-Ethyl-8,8-dimethyl-6,10-dioxaspiro[4.5]decan-2-one; 4-Ethyl-8,8-dimethyl-6,10-dioxaspiro[4.5]decan-2-one, (4R)-; (R)-4-Ethyl-8,8-dimethyl-6,10-dioxaspiro[4.5]decan-2-one; Spirocyclic ketal ketone; (4R)-4-Ethyl-8,8-dimethyl-1,7-dioxaspiro[5.5]undecan-2-one (alternative numbering); Chiral spiroketal intermediate
EINECS	Contact for details

Quality Control

Our production of 6,10-Dioxaspiro[4.5]Decan-2-One,4-Ethyl-8,8-Dimethyl-,(4R)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. All materials are characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.