Description

1H-Pyrrolo[1,2-A]Indole-1-Acetic Acid, 6-Fluoro-2,3-Dihydro-, Methyl Ester CAS NO 476619-16-6 is a high-purity, fluorinated indole derivative serving as a critical advanced pharmaceutical intermediate. This compound is valued for its precise molecular architecture, which is essential for synthesizing novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic frameworks and studying structure-activity relationships (SAR).
• Preclinical Development: Serves as a starting material or intermediate for producing compounds used in pharmacological screening and early-stage drug development.
• Chemical Reference Standard: Employed as a high-purity analytical standard for method development and quality control in API manufacturing.
• Agrochemical Research: Potential intermediate for developing new fluorinated agrochemicals due to the bioactivity imparted by the fluorine atom and indole core.
• Material Science Exploration: Investigated as a precursor for specialty organic electronic materials or fluorescent markers.

Basic Information

Product Name	1H-Pyrrolo[1,2-A]Indole-1-Acetic Acid, 6-Fluoro-2,3-Dihydro-, Methyl Ester
CAS No.	476619-16-6
Molecular Formula	C15H14FNO2
Molecular Weight	259.28 g/mol
Synonyms	6-Fluoro-2,3-dihydro-1H-pyrrolo[1,2-a]indole-1-acetic acid methyl ester; Methyl 6-fluoro-2,3-dihydro-1H-pyrrolo[1,2-a]indole-1-acetate; 6-Fluoro-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl-acetic acid methyl ester; 1H-Pyrrolo[1,2-a]indole-1-acetic acid, 6-fluoro-2,3-dihydro-, methyl ester; CAS 476619-16-6
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[1,2-A]Indole-1-Acetic Acid, 6-Fluoro-2,3-Dihydro-, Methyl Ester adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure compliance with exacting customer and research-grade specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.