Description

3-Amino-N,6-Diphenyl-4-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2-Carboxamide is a high-value, multifunctional heterocyclic compound featuring a thienopyridine core, strategically substituted with amino, phenyl, and trifluoromethyl groups. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile scaffold for medicinal chemistry research. It is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of potential drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries due to its privileged heterocyclic structure.
• Agrochemical Development: Employed in the research and synthesis of novel pesticides and herbicides, leveraging the bioactivity of the thienopyridine moiety.
• Organic Electronic Materials: Investigated as a precursor for organic semiconductors and light-emitting materials, where the conjugated system and substituents tune electronic properties.
• Chemical Biology Probes: Utilized in the development of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, functionalized heterocycles.

Basic Information

Product Name	3-Amino-N,6-Diphenyl-4-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2-Carboxamide
CAS No.	476484-00-1
Molecular Formula	C22H16F3N3OS
Molecular Weight	427.44 g/mol
Synonyms	3-Amino-N,6-diphenyl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide; Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-N,6-diphenyl-4-(trifluoromethyl)-; 476484-00-1; 3-Amino-4-(trifluoromethyl)-N,6-diphenylthieno[2,3-b]pyridine-2-carboxamide; 4-(Trifluoromethyl)-3-amino-N,6-diphenylthieno[2,3-b]pyridine-2-carboxamide
EINECS	Contact for details

Quality Control

Our 3-Amino-N,6-Diphenyl-4-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures a reliable supply of this high-purity intermediate for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.