Description

2-Pyrrolidinone, 1-[[2-(7-Bromo-4-Quinolinyl)-1-(6-Methyl-2-Pyridinyl)Ethylidene]Amino]- is a high-purity, advanced pharmaceutical intermediate designed for complex synthesis pathways. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs), particularly those targeting specific therapeutic areas. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Process Development & Scale-up: Serves as a critical raw material for developing robust and scalable manufacturing processes for APIs under Good Manufacturing Practice (GMP) conditions.
• Contract Synthesis: Supplied to CDMOs for custom synthesis projects requiring high-fidelity, structurally complex intermediates.
• Biochemical Research: Potential use as a specialized reagent or ligand in biochemical assays and probe development.

Basic Information

Product Name	2-Pyrrolidinone, 1-[[2-(7-Bromo-4-Quinolinyl)-1-(6-Methyl-2-Pyridinyl)Ethylidene]Amino]-
CAS No.	476473-60-6
Molecular Formula	C21H19BrN4O
Molecular Weight	423.31 g/mol
Synonyms	1-[[2-(7-Bromo-4-quinolinyl)-1-(6-methyl-2-pyridinyl)ethylidene]amino]-2-pyrrolidinone; 1-[(2-(7-Bromoquinolin-4-yl)-1-(6-methylpyridin-2-yl)ethylidene)amino]pyrrolidin-2-one; 476473-60-6; (E)-1-((2-(7-bromoquinolin-4-yl)-1-(6-methylpyridin-2-yl)ethylidene)amino)pyrrolidin-2-one; Advanced Brominated Quinoline-Pyridine Intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality systems suitable for pharmaceutical development. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, residual solvent analysis (GC), and identity confirmation (NMR, MS). We provide full traceability and detailed Certificates of Analysis (COA) to support your regulatory filings and ensure consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.