Description

Spiro[Naphthalene-2(1H),2-Oxiran]-1-Ol, 3-Ethyl-3,4-Dihydro-1-Methyl-, (1R,2S,3R)-Rel- (9Ci) is a complex, stereochemically defined spirocyclic oxirane derivative of naphthalene. This compound matters as a high-value, structurally sophisticated chiral building block for advanced organic synthesis, enabling the construction of intricate molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) or anti-inflammatory targets.
• Agrochemical Synthesis: Used in the creation of novel, stereoselective pesticides and herbicides where the specific spatial orientation of the molecule is critical for bioactivity.
• Advanced Material Precursor: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with unique optical or electronic properties.
• Asymmetric Catalysis Ligand Scaffold: Provides a complex, rigid backbone for the development of novel chiral ligands and organocatalysts.
• Academic & Institutional Research: Employed in universities and R&D institutes for methodological studies in stereoselective synthesis and natural product analog construction.
• Fine Chemical Production: Utilized in the multi-step synthesis of other high-value, complex specialty chemicals for various industrial applications.

Basic Information

Product Name	Spiro[Naphthalene-2(1H),2-Oxiran]-1-Ol, 3-Ethyl-3,4-Dihydro-1-Methyl-, (1R,2S,3R)-Rel- (9Ci)
CAS No.	476213-23-7
Molecular Formula	C₁₅H₁₈O₂
Molecular Weight	230.30 g/mol
Synonyms	rel-(1R,2S,3R)-3-Ethyl-3,4-dihydro-1-methylspiro[naphthalene-2(1H),2'-oxiran]-1-ol; (1R,2S,3R)-rel-3-Ethyl-1-methyl-1,2,3,4-tetrahydrospiro[naphthalene-2,2'-oxiran]-1-ol; 3-Ethyl-3,4-dihydro-1-methylspiro[naphthalene-2(1H),2'-oxiran]-1-ol, (1R,2S,3R)-rel-; Spirocyclic naphthalene oxiranol derivative; CAS 476213-23-7
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with typical purities of ≥95% to ≥98% (by HPLC), with enantiomeric excess (ee) confirmed for the specified stereochemistry. Certificates of Analysis (COA) detailing identity, purity (HPLC/GC), chiral purity, and residual solvent content are available upon request. Production can be aligned with cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be sensitive to moisture and oxidation; consider storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥95.0%
Chiral Purity (Chiral HPLC)	≥98.0% ee
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.