Description

Spiro[Naphthalene-2(1H),2-Oxiran]-1-One, 3-Ethyl-3,4-Dihydro-, (2R,3S)-Rel- (9Ci) is a high-purity, stereochemically defined spirocyclic oxirane derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique fused ring system and defined stereochemistry make it a valuable intermediate for constructing complex molecular architectures with precise three-dimensional control. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-cancer drug candidates.
• Agrochemical Synthesis: Building block for creating advanced pesticides and herbicides with enhanced efficacy and stereospecific activity.
• Asymmetric Catalysis Research: Valuable substrate or ligand precursor in the development and study of new asymmetric catalytic reactions.
• Material Science: Intermediate for synthesizing specialty polymers and advanced organic materials with specific optical or electronic properties.
• Academic & R&D Laboratories: Used in methodological studies and the synthesis of complex natural product analogs or novel chemical entities.

Basic Information

Product Name	Spiro[Naphthalene-2(1H),2-Oxiran]-1-One, 3-Ethyl-3,4-Dihydro-, (2R,3S)-Rel- (9Ci)
CAS No.	476213-20-4
Molecular Formula	C₁₄H₁₄O₂
Molecular Weight	214.26 g/mol
Synonyms	rel-(2R,3S)-3-Ethyl-3,4-dihydrospiro[naphthalene-2(1H),2'-oxiran]-1-one; 3-Ethyl-3,4-dihydro-1H-spiro[naphthalene-2,2'-oxiran]-1-one, (2R,3S)-rel-; Spiro[naphthalene-2(1H),2'-oxiran]-1-one, 3-ethyl-3,4-dihydro-, (2R,3S)-rel-; (rel)-(2R,3S)-3-Ethyl-1-oxo-3,4-dihydro-1H-spiro[naphthalene-2,2'-oxirane]; CAS 476213-20-4
EINECS	Contact for details

Quality Control

Our Spiro[Naphthalene-2(1H),2-Oxiran]-1-One, 3-Ethyl-3,4-Dihydro-, (2R,3S)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.