Description

Spiro[Furo[3,4-C]Pyridine-3(1H),4'-Piperidin]-1-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex spirocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in innovative drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of new therapeutic agents.
• Drug Discovery & Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization, especially for CNS targets.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for new API candidates.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in API manufacturing.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and novel synthetic methodologies.

Basic Information

Product Name	Spiro[Furo[3,4-C]Pyridine-3(1H),4'-Piperidin]-1-One Hydrochloride
CAS No.	475152-16-0
Molecular Formula	C11H14N2O2•HCl
Molecular Weight	242.70 g/mol (Free base: 206.24 g/mol)
Synonyms	1'-Oxospiro[furo[3,4-c]pyridine-3(1H),4'-piperidine] hydrochloride; Spiro(furo[3,4-c]pyridine-3(1H),4'-piperidin)-1-one hydrochloride; 1H-Spiro[furo[3,4-c]pyridine-3,4'-piperidin]-1-one hydrochloride; 475152-16-0; Furo[3,4-c]pyridine-3(1H)-spiro-4'-piperidin-1-one HCl; Spirocyclic furopyridine piperidinone hydrochloride
EINECS	Contact for details

Quality Control

Our Spiro[Furo[3,4-C]Pyridine-3(1H),4'-Piperidin]-1-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.