Description

1,4-Dioxaspiro[4.5]Dec-8-En-7-Ol is a versatile spirocyclic compound featuring both an enol and a dioxolane functional group, making it a valuable chiral building block and intermediate in advanced organic synthesis. Its unique fused-ring structure is critical for constructing complex molecular architectures with precise stereochemistry. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides where specific stereochemistry is required for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fragrance and Flavor Chemistry: Employed in the research and development of novel synthetic musk compounds and other specialty aroma chemicals.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers with unique thermal or mechanical properties.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including new cyclization and functionalization reactions.

Basic Information

Product Name	1,4-Dioxaspiro[4.5]Dec-8-En-7-Ol
CAS No.	475051-27-5
Molecular Formula	C9H12O3
Molecular Weight	168.19 g/mol
Synonyms	8-Hydroxy-1,4-dioxaspiro[4.5]dec-8-ene; 1,4-Dioxaspiro[4.5]dec-8-en-7-ol; 7-Hydroxy-1,4-dioxaspiro[4.5]dec-8-ene; Spiro[1,3-dioxolane-2,1'-cyclohex-4'-en]-4'-ol; Cyclohex-4-ene-1,1-diyl dimethanol cyclic acetal
EINECS	Contact for details

Quality Control

Our 1,4-Dioxaspiro[4.5]Dec-8-En-7-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool (15-25°C), dry place. Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed when not in use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.