Description

1,2-Dioleoyl-Sn-Glycero-3-Phosphoethanolamine, Dansyl-Labeled is a high-purity, fluorescently tagged phospholipid essential for advanced membrane biophysics and cell biology research. Its dansyl fluorophore provides a sensitive, environmentally responsive probe for studying lipid dynamics, membrane fusion, and protein-lipid interactions. This compound is critical for researchers and formulators in pharmaceutical development, diagnostic assay design, and advanced biomaterials science.

Application

• Membrane Biophysics Research: As a fluorescent probe for studying lipid bilayer properties, phase transitions, and membrane fluidity.
• Liposome & Nanoparticle Tracking: For labeling and real-time visualization of liposomal drug delivery systems and lipid nanoparticles (LNPs).
• Cell Biology & Microscopy: In fluorescence microscopy (e.g., FRAP, FLIM) to investigate cellular uptake, intracellular trafficking, and membrane organization.
• Protein-Lipid Interaction Studies: To detect and quantify the binding of membrane-associated proteins, peptides, or drugs to lipid surfaces.
• Diagnostic Assay Development: As a key component in fluorescence-based biosensors and assays for high-throughput screening.
• Model Membrane Systems: For constructing defined, fluorescently labeled supported lipid bilayers (SLBs) or giant unilamellar vesicles (GUVs).

Basic Information

Product Name	1,2-Dioleoyl-Sn-Glycero-3-Phosphoethanolamine, Dansyl-Labeled
CAS No.	474942-79-5
Molecular Formula	C73H121N2O9P
Molecular Weight	1201.73 g/mol
Synonyms	DOPE-Dansyl; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-(5-dimethylaminonaphthalene-1-sulfonyl); Dansyl-DOPE; N-(Dansyl)-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine; Fluorescent DOPE; N-(5-Dimethylaminonaphthalene-1-sulfonyl)-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine; DOPE labeled with dansyl; Phospholipid dansyl conjugate
EINECS	Contact for details

Quality Control

Our 1,2-Dioleoyl-Sn-Glycero-3-Phosphoethanolamine, Dansyl-Labeled is manufactured under strict quality systems to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, fluorescence characteristics, and absence of critical impurities. We adhere to cGMP principles for production and provide full traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and light-sensitive nature. For long-term stability, store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange waxy solid or film
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Fluorescence Properties	Excitation ~340 nm, Emission ~520 nm (solvent dependent)
Solubility	Chloroform, Methanol, Ethanol
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.