Description

(2-Amino-Pyridin-4-Ylmethyl)-Carbamic Acid tert-Butyl Ester is a high-purity, protected amine derivative crucial for advanced organic synthesis. This compound serves as a versatile and valuable building block for the development of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its pyridine-based structure.
• Peptidomimetics & PROTACs: The tert-butyloxycarbonyl (Boc) protected amine is instrumental in creating peptide analogs and Proteolysis Targeting Chimeras (PROTACs).
• Ligand Synthesis: Serves as a precursor for synthesizing specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological mechanisms and target engagement.
• Custom Synthesis: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) performing bespoke chemical synthesis.

Basic Information

Product Name	(2-Amino-Pyridin-4-Ylmethyl)-Carbamic Acid tert-Butyl Ester
CAS No.	474809-21-7
Molecular Formula	C11H17N3O2
Molecular Weight	223.27 g/mol
Synonyms	4-[[(tert-Butoxycarbonyl)amino]methyl]-2-aminopyridine; 2-Amino-4-[(Boc-amino)methyl]pyridine; tert-Butyl N-[(2-amino-4-pyridyl)methyl]carbamate; Boc-4-(aminomethyl)-2-aminopyridine; (2-Amino-4-pyridinylmethyl)carbamic acid 1,1-dimethylethyl ester; N-Boc-2-amino-4-aminomethylpyridine; 2-Amino-4-(Boc-aminomethyl)pyridine
EINECS	Contact for details

Quality Control

Our (2-Amino-Pyridin-4-Ylmethyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.