Description

1'-Benzylspiro[Indoline-3,4'-Piperidine] is a sophisticated spirocyclic organic compound featuring a unique indoline-piperidine hybrid structure. This complex heterocyclic scaffold is of significant value in modern pharmaceutical research and development, serving as a critical building block for medicinal chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel bioactive molecules targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel drug candidates, particularly in neuroscience and psychiatry.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in high-throughput screening.
• Ligand and Receptor Probe Development: Employed in the design and synthesis of selective ligands for studying neurotransmitter receptors and transporters.
• Agrochemical Research: Serves as a building block for developing new active ingredients with potential insecticidal or herbicidal properties.
• Chemical Biology Tool: Utilized to create molecular probes for investigating biological pathways and protein functions.
• Process Chemistry & Scale-Up: Acts as an intermediate in the optimization and commercial-scale production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1'-Benzylspiro[Indoline-3,4'-Piperidine]
CAS No.	474538-99-3
Molecular Formula	C20H22N2
Molecular Weight	290.41 g/mol
Synonyms	Spiro[indoline-3,4'-piperidine], 1'-benzyl-; 1'-Benzylspiro[indoline-3,4'-piperidine]; 1'-Benzyl-1,2-dihydrospiro[3H-indole-3,4'-piperidine]; 1'-Benzyl-1,2-dihydrospiro[indole-3,4'-piperidine]; 1'-Benzyl-2,3-dihydro-1H-spiro[indole-3,4'-piperidine]; 1'-Benzyl-1H-spiro[indole-3,4'-piperidine]; Benzylspiroindolinopiperidine; 474538-99-3
EINECS	Contact for details

Quality Control

Our 1'-Benzylspiro[Indoline-3,4'-Piperidine] is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity and impurity profiles. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.