Description

H-Pyrazolo[1,5-A]Pyridine-4-Carboxylic Acid CAS NO 474432-61-6 is a high-purity, nitrogen-containing heterocyclic carboxylic acid building block essential for advanced organic synthesis. This compound is valued for its rigid bicyclic scaffold and bifunctional reactivity, enabling the construction of complex molecular architectures. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in catalysis and metal-organic frameworks (MOFs) due to its nitrogen-rich structure.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers where its conjugated system is beneficial.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes in diagnostic and biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized heterocycles.

Basic Information

Product Name	H-Pyrazolo[1,5-A]Pyridine-4-Carboxylic Acid
CAS No.	474432-61-6
Molecular Formula	C7H4N2O2
Molecular Weight	148.12 g/mol
Synonyms	Pyrazolo[1,5-a]pyridine-4-carboxylic acid; 4-Pyrazolo[1,5-a]pyridinecarboxylic acid; 1H-Pyrazolo[1,5-a]pyridine-4-carboxylic acid; 474432-61-6; Pyrazolo[1,5-a]pyridine-4-carboxylic acid (9CI); SCHEMBL18805527; DTXSID90672979; BCP24733; ZINC000253899716; AKOS005258213.
EINECS	Contact for details

Quality Control

Our H-Pyrazolo[1,5-A]Pyridine-4-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all critical quality attributes. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.