Description

1-(4-Iodophenyl)-3-Morpholino-5,6-Dihydropyridin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. It is primarily sought by R&D and process development teams in the pharmaceutical, biotechnology, and fine chemical sectors for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted kinase inhibitors and other small molecule drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in vitro to study biological pathways and enzyme inhibition mechanisms.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.

Basic Information

Product Name	1-(4-Iodophenyl)-3-Morpholino-5,6-Dihydropyridin-2(1H)-One
CAS No.	473927-69-4
Molecular Formula	C15H17IN2O2
Molecular Weight	384.21 g/mol
Synonyms	1-(4-Iodophenyl)-3-morpholino-5,6-dihydro-2(1H)-pyridinone; 3-Morpholino-1-(4-iodophenyl)-5,6-dihydro-2(1H)-pyridinone; 1-(4-Iodophenyl)-3-(morpholin-4-yl)-5,6-dihydro-1H-pyridin-2-one; 473927-69-4; 4-(1-(4-Iodophenyl)-2-oxo-1,2,5,6-tetrahydropyridin-3-yl)morpholine
EINECS	Contact for details

Quality Control

Our production of 1-(4-Iodophenyl)-3-Morpholino-5,6-Dihydropyridin-2(1H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.