Description

2-{[(tert-Butoxycarbonyl)Amino]Methyl}Isonicotinic Acid is a high-purity, protected amino acid derivative that serves as a critical building block in modern organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular construction, particularly in the development of complex active pharmaceutical ingredients (APIs). It is primarily utilized by the pharmaceutical, agrochemical, and advanced materials industries for applications such as peptide synthesis, linker chemistry, and the creation of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those containing nicotinic acid or pyridine scaffolds.
• Peptide Chemistry: Used as a Boc-protected amino acid building block for solid-phase and solution-phase peptide synthesis (SPPS).
• Linker and Spacer Molecule: Employed in bioconjugation and the development of antibody-drug conjugates (ADCs) due to its functional handles.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides and insecticides with specific mode-of-action targets.
• Material Science: Utilized in the synthesis of functionalized polymers and ligands for catalysis.
• Chemical Biology Probes: Acts as a starting material for creating tagged molecules used in proteomics and diagnostic assay development.

Basic Information

Product Name	2-{[(tert-Butoxycarbonyl)Amino]Methyl}Isonicotinic Acid
CAS No.	473924-63-9
Molecular Formula	C12H16N2O4
Molecular Weight	252.27 g/mol
Synonyms	2-((Boc-amino)methyl)isonicotinic acid; 2-(((tert-Butoxycarbonyl)amino)methyl)pyridine-4-carboxylic acid; 2-(Boc-aminomethyl)isonicotinic acid; 4-Pyridinecarboxylic acid, 2-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-; Boc-AMINOMETHYL-ISONICOTINIC ACID; 2-[(tert-Butoxycarbonylamino)methyl]isonicotinic acid; 2-(N-Boc-aminomethyl)isonicotinic acid
EINECS	Contact for details

Quality Control

Our 2-{[(tert-Butoxycarbonyl)Amino]Methyl}Isonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.