Description

Cyclopropanecarboxylic Acid, 2,2-Dimethyl-, Ethyl Ester, (-)- (9Ci) is a high-purity chiral ester building block of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined cyclopropane ring, a structural motif prized for its ability to impart unique conformational and metabolic stability to target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, where precise stereochemistry is critical for efficacy.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in constructing advanced active ingredients for crop protection, where the cyclopropane moiety enhances biological activity and environmental stability.
• Asymmetric Catalysis & Ligand Development: Serves as a precursor or a chiral auxiliary in the development of new catalysts for stereoselective transformations.
• Fine Chemical & Flavor/Fragrance Building Block: Employed in the synthesis of complex, high-value specialty chemicals and aroma compounds requiring specific stereochemistry.
• Material Science Research: Investigated as a monomer or modifier for creating polymers with tailored thermal and mechanical properties.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2,2-Dimethyl-, Ethyl Ester, (-)- (9Ci)
CAS No.	473717-80-5
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	(-)-Ethyl 2,2-Dimethylcyclopropanecarboxylate; (1R)-2,2-Dimethylcyclopropanecarboxylic Acid Ethyl Ester; Ethyl (1R)-2,2-Dimethylcyclopropanecarboxylate; (R)-Ethyl 2,2-Dimethylcyclopropanecarboxylate; (R)-2,2-Dimethylcyclopropanecarboxylic Acid Ethyl Ester; (-)-2,2-Dimethylcyclopropanecarboxylic Acid Ethyl Ester; Chiral Ethyl Dimethylcyclopropanecarboxylate
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2,2-Dimethyl-, Ethyl Ester, (-)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.