Description

Diethyl (1-Trityl-1H-Imidazol-4-Yl)Methylphosphonate is a specialized organophosphonate building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the preparation of complex molecules, particularly those with potential biological activity. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel imidazole-based scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging the imidazole moiety's bioactivity.
• Ligand Synthesis: Serves as a starting material for creating sophisticated phosphonate-containing ligands used in catalysis and metal coordination chemistry.
• Chemical Biology Probes: Employed in the construction of molecular probes to study biological processes and enzyme mechanisms.
• Peptidomimetic Development: Facilitates the incorporation of phosphonate groups into peptide analogs to enhance stability and modulate biological activity.
• Material Science Research: Potential monomer or additive in the development of specialty polymers with unique properties.

Basic Information

Product Name	Diethyl (1-Trityl-1H-Imidazol-4-Yl)Methylphosphonate
CAS No.	473659-21-1
Molecular Formula	C29H31N2O3P
Molecular Weight	486.54 g/mol
Synonyms	Diethyl [(1-trityl-1H-imidazol-4-yl)methyl]phosphonate; Diethyl (1-Triphenylmethyl-1H-imidazol-4-yl)methylphosphonate; (1-Trityl-1H-imidazol-4-yl)methylphosphonic Acid Diethyl Ester; Phosphonic acid, P-[(1-trityl-1H-imidazol-4-yl)methyl]-, diethyl ester; Diethyl (1-Tritylimidazol-4-yl)methylphosphonate; 4-[(Diethoxyphosphoryl)methyl]-1-trityl-1H-imidazole
EINECS	Contact for details

Quality Control

Our Diethyl (1-Trityl-1H-Imidazol-4-Yl)Methylphosphonate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.