Description

Ethyl 4-(3-Bromophenyl)-2,4-Dioxobutanoate is a specialized organic building block characterized by its β-keto ester functionality and brominated aromatic ring. This compound is of significant value in synthetic organic chemistry, serving as a versatile precursor for constructing complex heterocyclic and pharmaceutical intermediates. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those containing heterocyclic cores like pyrazoles, isoxazoles, and pyridines.
• Agrochemical Research: Used in the development of new active ingredients for crop protection agents, leveraging its reactive sites for structural diversification.
• Material Science: Serves as a monomer or building block for creating specialized polymers and organic electronic materials.
• Chemical Synthesis: Employed in multi-step organic synthesis for C-C bond formation reactions, such as Claisen condensations and Michael additions.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and the discovery of new chemical entities.
• Fine Chemical Production: Acts as a starting material for the custom synthesis of high-value, low-volume specialty chemicals.

Basic Information

Product Name	Ethyl 4-(3-Bromophenyl)-2,4-Dioxobutanoate
CAS No.	473537-92-7
Molecular Formula	C12H11BrO4
Molecular Weight	299.12 g/mol
Synonyms	Ethyl 3-(3-Bromobenzoyl)pyruvate; 4-(3-Bromophenyl)-2,4-dioxobutanoic Acid Ethyl Ester; 3-(3-Bromobenzoyl)pyruvic Acid Ethyl Ester; Ethyl (3-Bromobenzoyl)pyruvate; 2,4-Dioxo-4-(3-bromophenyl)butanoic Acid Ethyl Ester; 1-Ethoxy-1,3-bis(3-bromophenyl)propane-1,3-dione (tautomeric form); β-Keto Ester Derivative
EINECS	Contact for details

Quality Control

Our Ethyl 4-(3-Bromophenyl)-2,4-Dioxobutanoate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.