Description

1H-Indazole-1-Carboxylic Acid,3-Bromo-5-Nitro-,1,1-Dimethylethyl Ester is a high-purity, protected indazole derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex heterocyclic scaffolds, enabling the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel indazole-based drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways.
• Material Science: Potential monomer or additive in the development of advanced polymers and functional organic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	1H-Indazole-1-Carboxylic Acid,3-Bromo-5-Nitro-,1,1-Dimethylethyl Ester
CAS No.	473416-22-7
Molecular Formula	C₁₃H₁₄BrN₃O₄
Molecular Weight	356.18 g/mol
Synonyms	tert-Butyl 3-bromo-5-nitro-1H-indazole-1-carboxylate; 3-Bromo-5-nitro-1H-indazole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-bromo-5-nitro-1H-indazole; Boc-3-bromo-5-nitroindazole; 3-Bromo-5-nitroindazole-1-carboxylic acid tert-butyl ester; tert-Butyl 3-bromo-5-nitroindazole-1-carboxylate; 1-Boc-3-bromo-5-nitroindazole
EINECS	Contact for details

Quality Control

Our 1H-Indazole-1-Carboxylic Acid,3-Bromo-5-Nitro-,1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area Percent)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.