Description

Cyclohexanecarboxylic Acid, 3-Hydroxy-, 1-Methylethyl Ester, (1S,3R)- is a high-purity, stereochemically defined chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its precise (1S,3R) configuration, which is critical for imparting specific biological activity and stereoselectivity in final target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel therapeutic agents, including central nervous system (CNS) drugs and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced, stereospecific pesticides and herbicides.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for enantioselective reactions.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals where stereochemical purity is paramount.
• Academic & Industrial R&D: A valuable reagent for methodological studies in synthetic organic chemistry and process development.
• Flavor & Fragrance Precursor: Potential use in the synthesis of complex, naturally-derived aroma compounds.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 3-Hydroxy-, 1-Methylethyl Ester, (1S,3R)-
CAS No.	472963-09-0
Molecular Formula	C10H18O3
Molecular Weight	186.25 g/mol
Synonyms	(1S,3R)-3-Hydroxycyclohexanecarboxylic Acid Isopropyl Ester; (1S,3R)-Isopropyl 3-Hydroxycyclohexanecarboxylate; (-)-Isopropyl (1S,3R)-3-Hydroxycyclohexanecarboxylate; (1S,3R)-HCCA-IP; trans-(-)-Isopropyl 3-Hydroxycyclohexanecarboxylate; (1S,3R)-3-Hydroxycyclohexanecarboxylic Acid 1-Methylethyl Ester; (1S,3R)-3-Hydroxy-1-cyclohexanecarboxylic Acid Isopropyl Ester
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 3-Hydroxy-, 1-Methylethyl Ester, (1S,3R)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high stereochemical purity (enantiomeric excess) and chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliable consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.