Description

Dimethyl n-tert-Butoxycarbonyl-3-Hydroxyaspartate, Mixture Of Diastereomers is a protected aspartic acid derivative, serving as a crucial chiral building block in advanced organic synthesis. This compound is valued for its role in introducing the hydroxyaspartate moiety under controlled conditions, enabling the construction of complex peptide mimetics and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of protease inhibitors, enzyme antagonists, and other pharmacologically active compounds.
• Peptidomimetic Research: Essential for constructing non-hydrolyzable peptide analogs and conformationally constrained amino acid residues in drug discovery.
• Chemical Biology Probes: Used in the development of activity-based probes and molecular tools to study biological pathways.
• Asymmetric Synthesis: Serves as a starting material or intermediate in stereoselective synthesis routes for natural products and complex organic molecules.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and high-value agrochemical intermediates.

Basic Information

Product Name	Dimethyl n-tert-Butoxycarbonyl-3-Hydroxyaspartate, Mixture Of Diastereomers
CAS No.	471242-81-6
Molecular Formula	C13H23NO7
Molecular Weight	305.32 g/mol
Synonyms	Dimethyl (2R,3S)- and (2S,3R)-3-Hydroxy-2-[(tert-butoxycarbonyl)amino]butanedioate; Boc-Asp(OMe)-OH(3-OH); 3-Hydroxy-N-Boc-L-aspartic Acid Dimethyl Ester (Diastereomeric Mixture); (2R,3S)- and (2S,3R)-Dimethyl 3-hydroxy-2-((tert-butoxycarbonyl)amino)succinate; Boc-3-hydroxy-Asp(OMe)-OMe; Dimethyl Boc-3-hydroxyaspartate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and diastereomeric ratio. Certificates of Analysis (COA) detailing specific parameters are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Diastereomeric Ratio (DR)	Specified per batch
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.