Description

2-Azabicyclo[2.2.0]Hex-5-En-3-One,2-Butyl-,(+)-(9Ci) is a high-purity, chiral bicyclic lactam building block of significant interest in advanced organic synthesis. Its unique constrained structure and defined stereochemistry make it a valuable intermediate for constructing complex molecular architectures, particularly in pharmaceutical research. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Asymmetric Synthesis: Employed as a building block for constructing complex, stereodefined molecules due to its rigid bicyclic framework and (+)-enantiomeric purity.
• Agrochemical Research: Used in the development of new, more effective pesticides and herbicides where specific stereochemistry is crucial for bioactivity.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Synthesis: Applied in the custom synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical fidelity.
• Academic Research: Utilized in universities and research institutes for methodological studies in organic chemistry and total synthesis projects.

Basic Information

Product Name	2-Azabicyclo[2.2.0]Hex-5-En-3-One,2-Butyl-,(+)-(9Ci)
CAS No.	470661-06-4
Molecular Formula	C9H13NO
Molecular Weight	151.21 g/mol
Synonyms	(+)-2-Butyl-2-azabicyclo[2.2.0]hex-5-en-3-one; 2-Butyl-2-azabicyclo[2.2.0]hex-5-en-3-one, (+)-; 2-n-Butyl-2-azabicyclo[2.2.0]hex-5-en-3-one; (1R,4S,5R)-2-Butyl-2-azabicyclo[2.2.0]hex-5-en-3-one; Bicyclic β-Lactam Derivative; Chiral Bicyclic Lactam; 2-Azabicyclo[2.2.0]hex-5-en-3-one, 2-butyl-, (1R,4S,5R)-
EINECS	Contact for details

Quality Control

Our 2-Azabicyclo[2.2.0]Hex-5-En-3-One,2-Butyl-,(+)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.