Description

Furan-3-Ylethynyltrimethylsilane is a high-value organosilicon building block featuring a furan ring and a protected acetylene moiety. This compound is essential for advanced organic synthesis, particularly in the construction of complex molecular architectures for pharmaceuticals and materials science. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as cross-coupling reactions and the synthesis of novel heterocyclic systems.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring furan-based or acetylene-linked structures.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that leverage its unique heterocyclic framework.
• Material Science Precursor: Serves as a monomer or building block for advanced polymers, conductive materials, and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: Employed in Sonogashira, Heck, and other palladium-catalyzed coupling reactions to form carbon-carbon bonds.
• Ligand Synthesis: Useful for creating specialized ligands for catalysis in asymmetric synthesis and transition metal complexes.
• Academic & Industrial R&D: A versatile reagent for exploring new synthetic methodologies and constructing complex organic molecules in research laboratories.

Basic Information

Product Name	Furan-3-Ylethynyltrimethylsilane
CAS No.	465521-19-1
Molecular Formula	C11H16OSi
Molecular Weight	192.33 g/mol
Synonyms	3-[(Trimethylsilyl)ethynyl]furan; Trimethyl(3-furanylethynyl)silane; 3-Furylacetylenyltrimethylsilane; 3-(Trimethylsilylethynyl)furan; Furan-3-yl-ethynyl-trimethyl-silane; 3-Ethynylfuran, trimethylsilyl derivative; TMS-ethynylfuran
EINECS	Contact for details

Quality Control

Our Furan-3-Ylethynyltrimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.