Description

2-Bromo-6-Isopropoxypyridine is a versatile halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of the bromine and isopropoxy groups, which enable selective functionalization and the construction of complex heterocyclic systems. This intermediate is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated nitrogen-containing ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting compounds.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig cross-coupling reactions to form biaryl and other complex structures.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological pathways and target engagement.

Basic Information

Product Name	2-Bromo-6-Isopropoxypyridine
CAS No.	463336-87-0
Molecular Formula	C8H10BrNO
Molecular Weight	216.08 g/mol
Synonyms	6-Isopropoxy-2-bromopyridine; 2-Bromo-6-(1-methylethoxy)pyridine; 2-Bromo-6-(propan-2-yloxy)pyridine; Pyridine, 2-bromo-6-(1-methylethoxy)-; 2-Bromo-6-isopropoxy-pyridine; 2-Br-6-iPrO-Py
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Isopropoxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to consistent quality and traceability supports your R&D and scale-up processes with reliable material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.