Description

3-Bromo-4-pyridinepropanoic acid ethyl ester is a high-purity brominated pyridine derivative, a crucial building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research and development. It serves as a key intermediate for medicinal chemists and process development scientists working on novel active ingredients.

Application

• Pharmaceutical Intermediate: A versatile synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides, leveraging the pyridine core's bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Useful for synthesizing labeled compounds and molecular probes for studying biological pathways and target engagement.

Basic Information

Item	Detail
Product Name	3-Bromo-4-pyridinepropanoic acid ethyl ester
CAS No.	463303-98-2
Molecular Formula	C10H12BrNO2
Molecular Weight	258.11 g/mol
Synonyms	Ethyl 3-bromo-4-pyridinepropanoate; 3-Bromo-4-(2-ethoxy-2-oxoethyl)pyridine; Ethyl 3-bromo-4-pyridinylpropionate; 3-Bromo-4-pyridinepropionic acid ethyl ester; β-(3-Bromo-4-pyridyl)propionic acid ethyl ester; 463303-98-2; Ethyl (3-bromopyridin-4-yl)acetate (common misnomer for propanoate derivative).
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-pyridinepropanoic acid ethyl ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.