Description

4-Pyridinecarbonitrile, 3-(5-Amino-2-Fluorophenyl)- is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which incorporates a pyridine nitrile moiety and a fluorinated aniline group, enabling precise molecular modifications. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand Synthesis: Serves as a versatile building block for creating complex ligands used in catalysis and material science.
• Fluorinated Compound Library: Essential for constructing diverse chemical libraries for high-throughput screening in drug discovery programs.
• Functional Material Development: Investigated for use in the synthesis of advanced organic electronic materials and specialty polymers.

Basic Information

Product Name	4-Pyridinecarbonitrile, 3-(5-Amino-2-Fluorophenyl)-
CAS No.	462652-71-7
Molecular Formula	C12H8FN3
Molecular Weight	213.21 g/mol
Synonyms	3-(5-Amino-2-fluorophenyl)isonicotinonitrile; 3-(5-Amino-2-fluorophenyl)-4-pyridinecarbonitrile; 5-Amino-2-fluoro-3-(4-cyanopyridin-3-yl)benzene; 3-(4-Cyanopyridin-3-yl)-5-fluoroanthranilonitrile; 3-(5-Amino-2-fluorophenyl)pyridine-4-carbonitrile; 4-Cyano-3-(5-amino-2-fluorophenyl)pyridine
EINECS	Contact for details

Quality Control

Our 4-Pyridinecarbonitrile, 3-(5-Amino-2-Fluorophenyl)- is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.