Description

4-Pyridinecarbonitrile, 3-(2-Fluoro-5-Nitrophenyl)- is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring a pyridine core with cyano, fluoro, and nitroaryl substituents, makes it a versatile intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought by pharmaceutical R&D and fine chemical sectors for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging its halogenated aromatic structure.
• Material Science: Serves as a building block for creating functional organic molecules used in electronic materials or liquid crystals.
• Chemical Synthesis: A versatile reagent for introducing the 3-(2-fluoro-5-nitrophenyl)pyridine-4-carbonitrile moiety into more complex molecular frameworks via cross-coupling or substitution reactions.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	4-Pyridinecarbonitrile, 3-(2-Fluoro-5-Nitrophenyl)-
CAS No.	462652-70-6
Molecular Formula	C12H6FN3O2
Molecular Weight	243.20 g/mol
Synonyms	3-(2-Fluoro-5-nitrophenyl)isonicotinonitrile; 3-(2-Fluoro-5-nitrophenyl)-4-cyanopyridine; 4-Cyano-3-(2-fluoro-5-nitrophenyl)pyridine; 3-(2-Fluoro-5-nitrophenyl)pyridine-4-carbonitrile; Isonicotinonitrile, 3-(2-fluoro-5-nitrophenyl)-; 462652-70-6; 3-(2-Fluoro-5-nitro-phenyl)-pyridine-4-carbonitrile
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure the integrity and consistency of our advanced intermediates. Each batch of 4-Pyridinecarbonitrile, 3-(2-Fluoro-5-Nitrophenyl)- is characterized and tested to meet exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. Our quality protocols are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.