Description

2-Bromo-3-Propoxypyridine is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its reactive bromine substituent and the directing influence of the pyridine nitrogen, enabling precise functionalization for complex molecule construction. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the pyridine core's bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl and heterobiaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein function.

Basic Information

Product Name	2-Bromo-3-Propoxypyridine
CAS No.	461661-44-9
Molecular Formula	C8H10BrNO
Molecular Weight	216.08 g/mol
Synonyms	3-Propoxy-2-bromopyridine; 2-Bromo-3-propoxy-pyridine; Pyridine, 2-bromo-3-propoxy-; 2-Bromopyridin-3-yl propyl ether
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Propoxypyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.