Description

Ethyl 3-{1-[(3-Chloro-4-Methylphenyl)Amino]-4-Cyano-3-Methylpyrido[1,2-A]Benzimidazol-2-Yl}Propanoate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development pipelines targeting specific therapeutic areas. It is primarily sought by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel benzimidazole-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Preclinical Studies: Serves as a critical material for producing compounds for pharmacological and toxicological evaluation.
• Custom Synthesis: A starting point for the development of proprietary compounds and libraries for high-throughput screening.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	Ethyl 3-{1-[(3-Chloro-4-Methylphenyl)Amino]-4-Cyano-3-Methylpyrido[1,2-A]Benzimidazol-2-Yl}Propanoate
CAS No.	459791-92-5
Molecular Formula	C25H22ClN5O2
Molecular Weight	459.93 g/mol
Synonyms	Ethyl 3-(1-((3-chloro-4-methylphenyl)amino)-4-cyano-3-methylpyrido[1,2-a]benzimidazol-2-yl)propanoate; 459791-92-5; UNII-7J7Q7T4K8R; 7J7Q7T4K8R; Ethyl 3-[1-[(3-chloro-4-methylphenyl)amino]-4-cyano-3-methylpyrido[1,2-a]benzimidazol-2-yl]propanoate; Propanoic acid, 3-[1-[(3-chloro-4-methylphenyl)amino]-4-cyano-3-methylpyrido[1,2-a]benzimidazol-2-yl]-, ethyl ester; SCHEMBL21806227; BCP31833
EINECS	Contact for details

Quality Control

Our Ethyl 3-{1-[(3-Chloro-4-Methylphenyl)Amino]-4-Cyano-3-Methylpyrido[1,2-A]Benzimidazol-2-Yl}Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a dry, inert atmosphere to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.