Description

6-Bromo-3-Isopropyl-[1,2,4]Triazolo[4,3-A]Pyridine is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for creating new chemical entities.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, and insecticides with specific biological activity.
• Ligand and Catalyst Development: The triazolopyridine core can be utilized to create novel ligands for metal catalysis and organocatalysis.
• Material Science Research: Potential precursor for the synthesis of organic electronic materials and photoactive compounds.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of complex molecules on a commercial scale.

Basic Information

Product Name	6-Bromo-3-Isopropyl-[1,2,4]Triazolo[4,3-A]Pyridine
CAS No.	459448-06-7
Molecular Formula	C9H10BrN3
Molecular Weight	240.10 g/mol
Synonyms	6-Bromo-3-(propan-2-yl)-[1,2,4]triazolo[4,3-a]pyridine; 3-Isopropyl-6-bromo-[1,2,4]triazolo[4,3-a]pyridine; 6-Bromo-3-isopropyl-1,2,4-triazolo[4,3-a]pyridine; 459448-06-7; Triazolopyridine Bromide Derivative; BTP Intermediate
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Isopropyl-[1,2,4]Triazolo[4,3-A]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the primary container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.