Description

1-[(5-Bromo-2-methoxyphenyl)sulfonyl]-4-methylpiperidine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct sulfonyl piperidine scaffold. This compound matters for its critical role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. Pharmaceutical companies, contract research organizations (CROs), and fine chemical manufacturers need it to develop new drug candidates targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Protease Inhibitor Development: The sulfonamide moiety makes it a candidate for incorporation into molecules designed to inhibit specific enzyme targets.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and protein function.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of complex, proprietary molecules for clients.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Item	Details
Product Name	1-[(5-Bromo-2-methoxyphenyl)sulfonyl]-4-methylpiperidine
CAS No.	459176-98-8
Molecular Formula	C13H18BrNO3S
Molecular Weight	348.26 g/mol
Synonyms	4-Methyl-1-[(5-bromo-2-methoxyphenyl)sulfonyl]piperidine; 1-(5-Bromo-2-methoxybenzenesulfonyl)-4-methylpiperidine; 4-Methyl-1-(5-bromo-2-methoxy-phenyl)sulfonyl-piperidine; 459176-98-8; 5-Bromo-2-methoxy-N-(4-methylpiperidin-1-yl)sulfonyl aniline (tautomeric form); 1-(5-Bromo-2-methoxyphenylsulfonyl)-4-methylpiperidine
EINECS	Contact for details

Quality Control

Our 1-[(5-Bromo-2-methoxyphenyl)sulfonyl]-4-methylpiperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.