Description

4-Piperidineaceticacid,α-Amino-,(Alphar)-(9Ci) is a high-purity chiral piperidine derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in chiral drug development. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high-quality, structurally defined intermediates for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel therapeutic agents, including central nervous system (CNS) drugs and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of advanced, enantiomerically pure pesticides and herbicides.
• Catalyst Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric catalysis.
• Peptidomimetics Research: Integral in medicinal chemistry for creating peptide analogs and conformationally restricted scaffolds.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis: A versatile starting point for contract research organizations (CROs) and CDMOs performing custom synthesis for clients.

Basic Information

Item	Details
Product Name	4-Piperidineaceticacid,α-Amino-,(Alphar)-(9Ci)
CAS No.	459166-02-0
Molecular Formula	C7H14N2O2
Molecular Weight	158.20 g/mol
Synonyms	(R)-2-Amino-2-(piperidin-4-yl)acetic acid; (αR)-α-Amino-4-piperidineacetic acid; 4-Piperidineacetic acid, α-amino-, (αR)-; (R)-4-Piperidylglycine; (R)-2-Amino-2-(4-piperidyl)acetic acid; (R)-Homo-4-piperidineglycine; (R)-2-(Piperidin-4-yl)glycine
EINECS	Contact for details

Quality Control

Every batch of 4-Piperidineaceticacid,α-Amino-,(Alphar)-(9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting standards for advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.