Description

4,5-Dimethyl-2-(Trimethylsilyl)Phenyl Trifluoromethanesulfonate is a specialized organosilicon reagent featuring a highly reactive triflate leaving group. This compound is a critical building block in advanced organic synthesis, particularly for the construction of complex molecules in pharmaceutical and materials science research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical, agrochemical, and advanced materials industries for demanding coupling and functionalization reactions.

Application

• Pharmaceutical Intermediate Synthesis: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for cross-coupling reactions like Suzuki, Negishi, and Stille couplings.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific aryl-silicon motifs.
• Materials Science & OLED Development: Serves as a monomer or functionalization agent in the creation of organic semiconductors, liquid crystals, and light-emitting materials.
• Ligand & Catalyst Preparation: Employed for the synthesis of sophisticated ligands and organometallic catalysts used in asymmetric synthesis.
• Polymer Functionalization: Used to introduce silyl-protected phenolic groups into polymer backbones to modify physical and chemical properties.
• Academic & Industrial R&D: A valuable tool for methodology development and exploring new reaction pathways in organic chemistry laboratories.

Basic Information

Product Name	4,5-Dimethyl-2-(Trimethylsilyl)Phenyl Trifluoromethanesulfonate
CAS No.	458566-99-9
Molecular Formula	C12H17F3O3SSi
Molecular Weight	326.41 g/mol
Synonyms	2-(Trimethylsilyl)-4,5-dimethylphenyl trifluoromethanesulfonate; 4,5-Dimethyl-2-(trimethylsilyl)phenyl triflate; (4,5-Dimethyl-2-(trimethylsilyl)phenyl) trifluoromethanesulfonate; 2-Trimethylsilyl-4,5-dimethylphenyl triflate; Trifluoromethanesulfonic acid 4,5-dimethyl-2-(trimethylsilyl)phenyl ester; 4,5-Dimethyl-2-trimethylsilylphenyl triflate; TMS-Dimethylphenyl Triflate
EINECS	Contact for details

Quality Control

Our 4,5-Dimethyl-2-(Trimethylsilyl)Phenyl Trifluoromethanesulfonate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.