Description

3-Amino-2,6-Dichloro-Isonicotinic Acid Ethyl Ester is a high-value pyridine derivative and a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated and amino-functionalized structure makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with specific modes of action.
• Ligand and Catalyst Development: Used to create complex chelating ligands for metal catalysts in asymmetric synthesis.
• Material Science Research: Intermediate for synthesizing functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-scale API development.

Basic Information

Product Name	3-Amino-2,6-Dichloro-Isonicotinic Acid Ethyl Ester
CAS No.	458543-81-2
Molecular Formula	C8H8Cl2N2O2
Molecular Weight	235.07 g/mol
Synonyms	Ethyl 3-Amino-2,6-dichloroisonicotinate; 2,6-Dichloro-3-aminopyridine-4-carboxylic Acid Ethyl Ester; 3-Amino-2,6-dichloro-4-pyridinecarboxylic Acid Ethyl Ester; 4-Pyridinecarboxylic acid, 3-amino-2,6-dichloro-, ethyl ester; Ethyl 3-amino-2,6-dichloro-4-pyridinecarboxylate; 458543-81-2; AI3-52344
EINECS	Contact for details

Quality Control

Our 3-Amino-2,6-Dichloro-Isonicotinic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.