Description

2-Pyridinepropanenitrile,α-Hydroxy-(9Ci) is a specialized organic nitrile derivative with a pyridine backbone, serving as a versatile chiral building block and intermediate in advanced synthetic chemistry. Its value lies in its unique molecular structure, which is critical for constructing complex pharmacologically active molecules and fine chemicals. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its nitrile and hydroxyl functionalities enable novel modes of action.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, dyes, and functional materials requiring precise molecular architecture.
• Academic and Industrial R&D: A valuable compound for methodological development in organic synthesis and medicinal chemistry research within university and corporate laboratories.

Basic Information

Product Name	2-Pyridinepropanenitrile,α-Hydroxy-(9Ci)
CAS No.	458528-64-8
Molecular Formula	C9H8N2O
Molecular Weight	160.17 g/mol
Synonyms	α-Hydroxy-2-pyridinepropanenitrile; 2-(1-Hydroxy-2-cyanoethyl)pyridine; (RS)-2-(1-Hydroxy-2-cyanoethyl)pyridine; 2-Pyridinepropanenitrile, α-hydroxy-; α-Hydroxy-2-pyridinepropionitrile; (2-Pyridyl)lactonitrile; 458528-64-8 (CAS); Hydroxy(pyridin-2-yl)acetonitrile (related structure).
EINECS	Contact for details

Quality Control

Every batch of 2-Pyridinepropanenitrile,α-Hydroxy-(9Ci) is produced under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA), which include results from HPLC, NMR, and other relevant spectroscopic and chromatographic methods. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.