Description

2-Amino-5-Trimethylsilanylethynylpyridine is a specialized organosilicon pyridine derivative that serves as a versatile building block in advanced organic synthesis. Its unique structure, featuring both an amino group and a trimethylsilylethynyl moiety, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for applications such as ligand synthesis and the development of functionalized polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research.
• Ligand Synthesis: Used in the preparation of sophisticated ligands for catalysis, including those for cross-coupling reactions.
• Agrochemical Research: Serves as a building block for creating new crop protection agents and herbicides.
• Materials Science: Employed in the synthesis of functionalized polymers, dendrimers, and advanced organic electronic materials.
• Chemical Biology Probes: Useful for creating tagged molecules and probes for studying biological systems.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	2-Amino-5-Trimethylsilanylethynylpyridine
CAS No.	457628-40-9
Molecular Formula	C11H16N2Si
Molecular Weight	204.35 g/mol
Synonyms	2-Amino-5-((trimethylsilyl)ethynyl)pyridine; 5-((Trimethylsilyl)ethynyl)pyridin-2-amine; 2-Pyridinamine, 5-[(trimethylsilyl)ethynyl]-; 2-Amino-5-(trimethylsilylethynyl)pyridine; 2-Amino-5-(trimethylsilylethinyl)pyridine; 5-(Trimethylsilylethynyl)pyridin-2-amine
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Trimethylsilanylethynylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our commitment to quality assurance ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.