Description

Methyl 4-Amino-3-(Trifluoromethoxy)Benzoate is a high-value, multi-functional chemical intermediate characterized by its benzoate ester core, amino group, and trifluoromethoxy substituent. This unique structure makes it a critical building block for synthesizing advanced molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its aromaticity and functional groups.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific properties such as improved thermal stability, chemical resistance, or unique surface characteristics.
• Dye & Pigment Intermediate: Utilized in the production of complex dyes and high-performance pigments, where the amino group facilitates chromophore development.
• Research & Development: Essential for academic and industrial research in medicinal chemistry, material science, and synthetic methodology development.

Basic Information

Product Name	Methyl 4-Amino-3-(Trifluoromethoxy)Benzoate
CAS No.	457097-93-7
Molecular Formula	C9H8F3NO3
Molecular Weight	235.16 g/mol
Synonyms	Methyl 4-amino-3-(trifluoromethoxy)benzoate; Benzoic acid, 4-amino-3-(trifluoromethoxy)-, methyl ester; 4-Amino-3-(trifluoromethoxy)benzoic acid methyl ester; Methyl 4-amino-α,α,α-trifluoro-m-anisate; 3-(Trifluoromethoxy)-4-aminobenzoic acid methyl ester; Methyl 3-(trifluoromethoxy)-4-aminobenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Amino-3-(Trifluoromethoxy)Benzoate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your specific R&D or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be stored away from direct light exposure. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.