Description

n-(Methoxymethyl)-2-Methyl-n-[(Trimethylsilyl)-Methyl]-2-Propanamine is a specialized organosilicon amine compound featuring both methoxymethyl and trimethylsilylmethyl protecting groups. This unique bifunctional structure makes it a valuable intermediate for advanced organic synthesis, particularly in the development of pharmaceuticals and complex fine chemicals. It is primarily used by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require high-purity, functionalized building blocks for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring silicon-containing or protected amine functionalities.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where its structural motifs can impart specific biological activity or stability.
• Ligand and Catalyst Preparation: Acts as a precursor for creating specialized nitrogen-containing ligands used in asymmetric catalysis and transition metal complexes.
• Polymer and Material Science: Employed in the synthesis of functionalized polymers, silicones, and advanced materials where the amine and silyl groups can modify surface properties or reactivity.
• Protecting Group Chemistry: Utilized in multi-step organic synthesis where the methoxymethyl (MOM) and trimethylsilylmethyl groups act as protective groups for amines, allowing for selective reactions at other sites.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process chemistry in exploring new synthetic routes and molecular entities.

Basic Information

Product Name	n-(Methoxymethyl)-2-Methyl-n-[(Trimethylsilyl)-Methyl]-2-Propanamine
CAS No.	455954-96-8
Molecular Formula	C10H25NOSi
Molecular Weight	203.40 g/mol
Synonyms	N-(Methoxymethyl)-N-[(trimethylsilyl)methyl]-2-methylpropan-2-amine; 2-Propanamine, N-(methoxymethyl)-2-methyl-N-[(trimethylsilyl)methyl]-; N-Methoxymethyl-N-(trimethylsilylmethyl)-tert-butylamine; tert-Butyl(methoxymethyl)((trimethylsilyl)methyl)amine; (Methoxymethyl)((trimethylsilyl)methyl)(tert-butyl)amine; N-(tert-Butyl)-N-(methoxymethyl)-1-(trimethylsilyl)methanamine
EINECS	Contact for details

Quality Control

Our n-(Methoxymethyl)-2-Methyl-n-[(Trimethylsilyl)-Methyl]-2-Propanamine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including chromatography and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.